1-way anova with bonferroni’s posttest  (GraphPad Software Inc)

Journal:

Article Title: Neonatal Colon Insult Alters Growth Factor Expression and TRPA1 Responses in Adult Mice

doi: 10.1016/j.pain.2010.08.029

Figure Lengend Snippet: NCI on postnatal days 8 and 10 produces visceral hypersensitivity in adulthood. A) Examples of EMG recordings of the VMR to graded balloon distension of the colon in naive (left) and NCI mice (right). B) Graph depicting the VMR of adult naive (black), NCI on P8 only (gray) and NCI on P8 and 10 (open) mice at increasing balloon pressures. NCI on P8 and 10 resulted in significantly higher VMR than NCI on P8 or naive (P < 0.05, two-way ANOVA), particularly at the highest pressures measured (* P < 0.05, ** P < 0.01 Bonferroni’s posttest). C) Treating neonatal mice with a perianal application of water-based lubricant (with or without intracolonic saline) did not influence the VMR during adulthood.

Article Snippet: Calculations were made using Microsoft Excel and statistical analysis was performed using 1-way or 2-way repeated measures analysis of variance (ANOVA) followed by Bonferroni’s posttest (GraphPad Prism, GraphPad Software, La Jolla, CA).

Techniques: Saline

Journal:

Article Title: Neonatal Colon Insult Alters Growth Factor Expression and TRPA1 Responses in Adult Mice

doi: 10.1016/j.pain.2010.08.029

Figure Lengend Snippet: NCI increases mechanical sensitivity in the hindpaw of adult mice. A) No differences in thermal sensitivity were observed between naive mice and those treated with MO, saline or only lubricant as neonates. B) NCI mice had a significantly higher paw withdrawal frequency to a 1g von Frey monofilament than naive mice (P < 0.05, one way ANOVA and Bonferroni’s posttest).

Article Snippet: Calculations were made using Microsoft Excel and statistical analysis was performed using 1-way or 2-way repeated measures analysis of variance (ANOVA) followed by Bonferroni’s posttest (GraphPad Prism, GraphPad Software, La Jolla, CA).

Techniques: Saline

Journal:

Article Title: Neonatal Colon Insult Alters Growth Factor Expression and TRPA1 Responses in Adult Mice

doi: 10.1016/j.pain.2010.08.029

Figure Lengend Snippet: NCI increases growth factor mRNA expression in the colon. Growth factor mRNA was measured prior to and following NCI. A) On P8, the colon expresses significantly higher levels of all growth factors examined, compared to adult mice (*** P < 0.0001, two-way ANOVA and Bonferroni’s posttest). All levels remained significantly elevated on P14, but were not significantly different from adult by P18. B) Comparisons between naive and NCI mice at each timepoint revealed a significant elevation in NGF, NT-3 and GDNF mRNA expression on P18 in NCI mice (** P < 0.01, *** P < 0.0001 vs. naive, two-way ANOVA and Bonferroni’s posttest).

Article Snippet: Calculations were made using Microsoft Excel and statistical analysis was performed using 1-way or 2-way repeated measures analysis of variance (ANOVA) followed by Bonferroni’s posttest (GraphPad Prism, GraphPad Software, La Jolla, CA).

Techniques: Expressing